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For research use only.

Verified Samples Verified Samples in IHC: Human liver cirrhosis, Human breast carcinoma
Verified Samples in IF: HepG2
Dilution IHC-P 1:50-1:200,  ICC/IF 1:20-1:100,  
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC-P,  ICC/IF
Clonality Rabbit Monoclonal
Immunogen Recombinant Human PIGR protein
Abbre PIGR
Synonyms Hepatocellular carcinoma-associated protein TB,  PIGR,  Polymeric immunoglobulin receptor,  Hepatocellular carcinoma-associated protein TB6,  Secretory component,  Poly-Ig receptor
Swissprot
Cellular Localization Cell membrane, Secreted.
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Immunology
Clone No. 12G8
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background The human polymeric immunoglobulin receptor (pIgR; also known as membrane secretory component) is an approximately 100 kDa type I transmembrane glycoprotein that is synthesized as a 764 amino acid (aa) precursor. It includes a signal sequence (aa 1-18), an extracellular region (aa 19-638), a transmembrane segment (aa 639-661), and a cytoplasmic domain (aa 662-764) . The extracellular region consists of five Ig-like domains and a sixth non-Ig domain that connects to the membrane region. pIgR is expressed on secretory epithelial cells of exocrine tissues. Immunoglobulin isotypes consist of two heavy (H) and two light (L) chains. F
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Unconjugated

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