Recombinant Nicastrin/NCSTN Monoclonal Antibody (AN300390P)
For research use only.
| Verified Samples | Verified Samples in IF: Hela |
| Dilution | ICC/IF 1:20-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | ICC/IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human Nicastrin/NCSTN protein |
| Abbre | NCSTN |
| Synonyms | UNQ, PRO, ATAG, KIAA, RP11 517F, Anterior pharynx defective, RP11517F, NCSTN, ATAG1874, nicastrin, Anterior pharynx defective 2, APH 2, APH2, NCT, NICA, RP11 517F10.1, RP11517F101, KIAA0253, UNQ1874, PRO4317, RP11-517F10.1 |
| Swissprot | |
| Tissue Specificity | Detected in brain (at protein level) |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Neuroscience, Stem Cells |
| Clone No. | 12F4 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
Other Clones
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Unconjugated
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