Recombinant Neurofilament (NF-L) Monoclonal Antibody (AN301288L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human brain |
| Dilution | IHC 1:2000-1:10000 |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human Neurofilament (NF-L) protein |
| Abbre | Neurofilament |
| Synonyms | PPP1R, NEFL, CMT1F, CMT2E, NF-L, NF68, NFL, PPP1R110, 68 kDa neurofilament protein, CMTDIG, light polypeptide, neurofilament, neurofilament light, FLJ53642, Neurofilament Light Polypeptide, Neurofilament triplet L protein, 68kDa Neurofilament, 68kDa Neurofilament, CMT1F, CMT2E, FLJ53642, Neurofilament Light Polypeptide, Neurofilament triplet L protein, NFL, NF-L, NF-L |
| Swissprot | |
| Cellular Localization | Cytoplasmic |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Neuroscience, Signal Transduction, Stem Cells, Developmental Biology |
| Clone No. | 4D5 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
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Unconjugated
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