Recombinant MUC1 Monoclonal Antibody (AN300416P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human breast, Human kidney, Human squamous cell carcinoma |
| Dilution | IHC-P 1:100-1:500 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human MUC1 Protein |
| Abbre | MUC1 |
| Synonyms | MAM, CA 15, MUC, ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, MUC1, CA15-3, mucin-1, CA15 3, CA153, Episialin, Carcinoma associated mucin, MUC 1, MUC1 beta, MUC1 CT, MUC1 NT, Mucin 1, Peanut reactive urinary mucin, Polymorphic epithelial mucin, Tumor associated mucin, MUC1/CA15-3 C-terminal, EMA, mucin 1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, Carcinoma-associated mucin, Krebs von den Lungen-6, Peanut-reactive urinary mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin |
| Swissprot | |
| Cellular Localization | Secreted, Cell membrane. Cytoplasm. Nucleus. |
| Tissue Specificity | Expressed on the apical surface of epithelial cells, especially of airway passages, breast and uterus. Also expressed in activated and unactivated T-cells. Overexpressed in epithelial tumors, such as breast or ovarian cancer and also in non-epithelial tumor cells. Isoform Y is expressed in tumor cells only. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Tags & Cell Markers, Signal Transduction, Cancer |
| Clone No. | 5D15 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | MUC-1 (Mucin-1; also PEM, PEMT, Episialin, tumor-associated mucin, and carcinoma associated mucin) is a 240-450 kDa type I transmembrane glycoprotein. Human MUC-1 is 1255 amino acids (aa) in length and contains a 23 aa signal sequence, a 1135 aa extracellular domain (ECD), a 23 aa transmembrane segment, and a 74 aa cytoplasmic tail. The ECD consists of degenerate tandem repeats and a tandem repeat region, which makes up the major portion of the protein. Potential O-glycosylation sites (serines and threonines) make up more than one-fourth of the amino acids. Splicing variants produce ten isoforms for human MUC-1. Human MUC-1 is 28% aa identical to mouse MUC-1. |
Other Clones
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Unconjugated
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