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Recombinant Mouse TPBG/5T4 (C-6His) (PKSM041401)

All Size Price Qty
50μg $ 198.00
10μg $ 88.00
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For research use only.

Synonyms 5T4 Protein, 5T4AG Protein, Human, M6P1 Protein, WAIF1 Protein
Species Mouse
Expression Host HEK293 Cells
Sequence Ser32-Ser361
Accession Q9Z0L0
Calculated Molecular Weight 36.6 kDa
Observed Molecular Weight 50-70 kDa
Tag C-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Not Applicable
Background Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
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Biotinylated

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