Recombinant Mouse Serpin E1/PAI-1 Protein (His Tag) (PKSM041124)
For research use only.
| Synonyms | Endothelial plasminogen activator inhibitor, Mr1, Pai1, Planh1, Plasminogen activator inhibitor 1, Serpin E1 |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Phe22-Pro402 |
| Accession | G5E899 |
| Calculated Molecular Weight | 43.7 kDa |
| Observed Molecular Weight | 50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation |
Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, 5% Mannitol, 0.02% Tween 80, 1mM EDTA, pH7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. |
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