Recombinant Mouse S100A8/CAGA Protein (His Tag) (PKSM041133)
For research use only.
| Synonyms | 60B8Ag, AI323541, B8Ag, CFAg, CP, Caga, Calgranulin-A, Chemotactic cytokine CP-10, Leukocyte L1 complex light chain, MRP-8, Migration inhibitory factor-related protein 8, Mrp8, Pro-inflammatory S100 cytokine, Protein S100-A8, S100 calcium-binding protein A8, S100a8 |
| Species | Mouse |
| Expression Host | E.coli |
| Sequence | Met1-Glu89 |
| Accession | P50115 |
| Calculated Molecular Weight | 11.3 kDa |
| Observed Molecular Weight | 13 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation |
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. |
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