Recombinant Mouse Interleukin-2/IL-2 Protein (active) (PKSM041523)
For research use only.
| Synonyms | Interleukin-2, IL-2, T-Cell Growth Factor, TCGF, Aldesleukin |
| Species | Mouse |
| Expression Host | HEK293 cells |
| Sequence | Ala21-Gln169 |
| Accession | P04351 |
| Calculated Molecular Weight | 18.07 kDa |
| Observed Molecular Weight | 22-25 kDa |
| Tag | C-His |
| Bio-activity | Measured in a cell proliferation assay using HT-2 mouse T cells. The ED50 for this effect is 0.88-3.5 ng/mL, corresponding to a specific activity of 2.86×105-1.14×106 units/mg. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | ≤0.1 EU per μg by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes. |
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