Recombinant Mouse Cyclophilin A Protein (PKSM041227)
For research use only.
| Synonyms | CYPA , Cyclophilin A, Cyclosporin A-binding protein, PPIA, PPIase A, Peptidyl-prolyl cis-trans isomerase A, Rotamase A, SP18 |
| Species | Mouse |
| Expression Host | E.coli |
| Sequence | Met1-Leu164 |
| Accession | P17742 |
| Calculated Molecular Weight | 18.0 kDa |
| Observed Molecular Weight | 16 kDa |
| Tag | None |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4. |
| Reconstitution | Not Applicable |
| Background | Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins(CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. |
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