Recombinant Mouse CXCL16 protein(His Tag) (PKSM041520)
For research use only.
| Synonyms | 9330140G23, ARMETL1, Arme |
| Species | Mouse |
| Expression Host | E.coli |
| Sequence | Asn 27-Pro 114 |
| Accession | Q8BSU2 |
| Calculated Molecular Weight | 10.7 kDa |
| Observed Molecular Weight | 11-17 kDa |
| Tag | N-His |
| Bio-activity | Measure by its ability to chemoattract BaF3 cells transfected with mouse CXCR6The ED50 for this effect is <3 ng/mL. |
| Purity | > 98 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation |
Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | CXCL16 is a single-pass type I membrane protein, which consists of 246 amino acids, CXCL16 induces a strong chemotatic response and calcium mobilization. CXCL16 acts as a scavenger receptor on macrophages, which specially binds to oxidized low density lipoprotein. CXCL16 may involves in pathophysiology such as atherogenesis. Soluble CXCL16 may play an important role in liver metastases through the induction of epithelial-mesenchymal transition. |
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