Recombinant Mouse CD74 Protein (mFc & His Tag) (PKSM041039)
For research use only.
| Synonyms | CD74 antigen, CD74 molecule, Cluster of Differentiation 74, DHLAG gamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, HLADG, class II invariant chain, major histocompatibility complex |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Gln56-Leu215 |
| Accession | P04441-2 |
| Calculated Molecular Weight | 44.5 kDa |
| Observed Molecular Weight | 45-55 kDa |
| Tag | C-mFc-His |
| Bio-activity | Not validated for activity |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5. |
| Reconstitution | Not Applicable |
| Background | Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. |
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