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For research use only.
| Synonyms | Bcm, sgp, HM48, BLAST, SLAMF, BCM1 surface antigen, BLAST-1, CD48 antigen, HM48-1, MRC OX-45 surface antigen, sgp-60, SLAMF2, Bcm-1, Cd48, BCM1, Sgp-60, AI449234, AW610730, BCM1, BLAST1, MEM-102, SLAM Family Member 2 |
| Species | Mouse |
| Expression Host | Mammalian |
| Sequence | Phe23-Ser217 |
| Accession | P18181 |
| Calculated Molecular Weight | 21.3 kDa |
| Observed Molecular Weight | 40-45 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses. |
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