Recombinant Mouse AGR3 Protein (His Tag) (PKSM041359)
For research use only.
| Synonyms | AG3, AGR3, Anterior gradient protein 3, BCMP11 |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Ile21-Leu165 |
| Accession | Q8R3W7 |
| Calculated Molecular Weight | 18.1 kDa |
| Observed Molecular Weight | 15-19 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH7.4. |
| Reconstitution | Not Applicable |
| Background | Anterior gradient protein 3 (AGR3) is an 18 kDa member of the AGR family of proteins. It is expressed in the ciliated cells of the airway epithelium, not detected in the mucous cells. Mature human AGR3 shares 92% amino acid sequence identity with mouse AGR3. It is required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. AGR3 might be involved in the regulation of intracellular calcium in tracheal epithelial cells. |
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