Recombinant Insulin Monoclonal Antibody (AN300052P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human pancreas |
| Dilution | IHC-P 1:200-1:1000, |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Rabbit Monoclonal |
| Immunogen | Recombinant Human Insulin Protein |
| Abbre | INS |
| Synonyms | MODY, IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10, INS, Insulin, Connecting Peptide, Insulin A chain, Insulin B chain, Preproinsulin, Proinsulin, Proinsulin precursor, IDDM, IDDM1, IDDM2, ILPR, ins, INS, Insulin A chain, Insulin B chain, IRDN, MODY10, Preproinsulin, Proinsulin, Proinsulin precursor, Pro-Insulin |
| Swissprot | |
| Cellular Localization | Secreted |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Signal Transduction, Neuroscience, Cardiovascular, Metabolism |
| Clone No. | 2C8 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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