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100μL $ 320.00
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For research use only.

Verified Samples Verified Samples in IHC: Human pancreas
Dilution IHC-P 1:200-1:1000,  
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC-P
Clonality Rabbit Monoclonal
Immunogen Recombinant Human Insulin Protein
Abbre INS
Synonyms MODY,  IDDM,  IDDM1,  IDDM2,  ILPR,  IRDN,  MODY10,  INS,  Insulin,  Connecting Peptide,  Insulin A chain,  Insulin B chain,  Preproinsulin,  Proinsulin,  Proinsulin precursor,  IDDM,  IDDM1,  IDDM2,  ILPR,  ins,  INS,  Insulin A chain,  Insulin B chain,  IRDN,  MODY10,  Preproinsulin,  Proinsulin,  Proinsulin precursor,  Pro-Insulin
Swissprot
Cellular Localization Secreted
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Signal Transduction,  Neuroscience,  Cardiovascular,  Metabolism
Clone No. 2C8
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
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Unconjugated

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