Recombinant Human VEGF Protein(His Tag) (PDMH100446)
For research use only.
| Synonyms | MVCD, Vascular Endothelial Growth Factor Isoform, VEGFA, MVCD1, VEGF, VPF, L VEGFA, VEGF A, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, Vascular Endothelial Growth Factor Isoform 165, Vascular permeability factor, VEGF121, VEGF165, VEGF-165, VEGF-A, Vascular endothelial growth factor A, Vascular permeability factor (VPF), MVCD1, vascular endothelial growth factor A, VEGF, VPF, MGC70609, vascular endothelial growth factor, vascular endothelial growth factor A121, vascular endothelial growth factor A165, VEGF120 |
| Species | Human |
| Expression Host | Mammalian |
| Sequence | Met1-Arg165 |
| Accession | P15692 |
| Calculated Molecular Weight | 18 kDa |
| Observed Molecular Weight | 18-24 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
| Background | Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor. |
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