Recombinant Human SULT1A1 Protein (His Tag) (PKSH033358)

For research use only.
Synonyms | Aryl sulfotransferase 1, HAST1/HAST2, OK/SW-cl.88, P-PST 1, Phenol Sulfotransferase 1, Phenol-Sulfating Phenol Sulfotransferase 1, ST1A1, ST1A3, STP, STP1, SULT1A1, Sulfotransferase 1A1, Thermostable Phenol Sulfotransferase, Ts-PST |
Species | Human |
Expression Host | E.coli |
Sequence | Met 1-Leu295 |
Accession | AAH00923.1 |
Calculated Molecular Weight | 35.6 kDa |
Observed Molecular Weight | 32 kDa |
Tag | N-His |
Bio-activity | Not validated for activity |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 10% Trehalose, 50mM Nacl, 0.05% Tween 80, pH7.8. |
Reconstitution | Not Applicable |
Background | Sulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver; lung; adrenal; brain; platelets; and skin. SULT1A1 is a phenol sulfotransferases with thermostable enzyme activity. SULT1A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines; phenolic drugs and neurotransmitters. It is responsible for the sulfonation and activation of minoxidil. SULT1A1 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. |
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