Recombinant Human SQSTM1/ p62 protein (His Tag) (PDEH100901)
For research use only.
| Synonyms | A170, DMRV, EBI 3 associated protein p60, EBIAP, FTDALS3, ORCA, OSF-6, OSIL, P62b, PDB 3, PDB3, SQSTM 1, STAP, STONE14, Sequestosome 1, ZIP3, p60 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ser3-Lys102 |
| Accession | Q13501 |
| Calculated Molecular Weight | 10.9 kDa |
| Observed Molecular Weight | 15 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. |
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