Recombinant Human Sell Protein(His Tag) (PDMH100243)
For research use only.
| Synonyms | A.11, AI528707, CD62 antigen ligand, CD62 antigen-like family member L, CD62L, gp90-MEL, IgA nephropathy, susceptibility to, included, L Selectin, L-selectin, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lnhr, LSEL, Ly-22, Ly-m22, Lyam-1, LYAM1, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, Lymphocyte antigen 22, Lymphocyte surface MEL-14 antigen, MEL-14, Pln homing receptor, PLNHR, Selectin L, Selectin, lymphocyte, SELL, TQ1 |
| Species | Human |
| Expression Host | Mammalian |
| Sequence | Trp39-Asn332 |
| Accession | P14151 |
| Calculated Molecular Weight | 32.2 kDa |
| Observed Molecular Weight | 50-70 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with an various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. |
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