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Recombinant Human PPM1G/PP2C-gamma Protein (aa 317-546, His Tag) (PKSH031182)

All Size Price Qty
100μg $ 760.00
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For research use only.

Synonyms PP2C-Gamma, PP2CG, PP2CGAMMA, PPM1G, Protein Phosphatase 1C, Protein Phosphatase 1G, Protein Phosphatase 2C Isoform Gamma, Protein Phosphatase Magnesium-Dependent 1 Gamma
Species Human
Expression Host E.coli
Sequence Met 317-Asp 546
Accession O15355
Calculated Molecular Weight 26.6 kDa
Observed Molecular Weight 30 kDa
Tag N-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin Please contact us for more information.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 50mM Tris, 1mM DTT, 20% glycerol, pH 7.5
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background Protein phosphatase 1G; also known as Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; PP2C-gamma; PPM1G and PPM1C; is a cytoplasm protein which belongs to thePP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis; skeletal muscle; and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress response pathways. PPM1G / PP2C-gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors; which is important for the formation of functional spliceosome. PPM1G / PP2C-gamma also plays a role in regulating cell cycle progression.
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