Recombinant Human PODXL Protein(GST Tag) (PDEH100646)
For research use only.
| Synonyms | Podocalyxin-like protein, PODXL, Gp200, PC, PCLP, PCLP-1, GCTM-2 antigen, GCTM, Gp200MGC138240, PCLP1, PCpodocalyxin, Podocalyxin, podocalyxin-like, PCLPGCTM-2 antigen, POD XL, Podocalyxin-like protein 1, Gp200, PCLP, PCLP 1, PCLP1, Podocalyxin, podocalyxin like, Podocalyxin like protein 1, PODXL, RCC marker, Renal Cell Carcinoma marker, TRA 1 81, TRA-1-60, GCTM 2 antigen, TRA 1 60 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ser23-Leu428 |
| Accession | O00592 |
| Calculated Molecular Weight | 70.6 kDa |
| Observed Molecular Weight | 78 kDa |
| Tag | N-GST |
| Bio-activity | Not validated for activity |
| Purity | > 80% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
| Background | Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer. |
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