Recombinant Human Placental Alkaline Phosphatase 1/ALPP Protein (His Tag) (PKSH032058)
For research use only.
| Synonyms | ALPP and PLAP, Alkaline phosphatase, Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, placental type |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ile23-Asp506 |
| Accession | P05187 |
| Calculated Molecular Weight | 53.7 kDa |
| Observed Molecular Weight | 60-85 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.2mM CaCl2, 10% Glycerol, pH 7.5. |
| Reconstitution | Not Applicable |
| Background | ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research. |
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