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Recombinant Human PIGR/SC protein (His Tag) (PDEH100808)

All Size Price Qty
500μg $ 1440.00
100μg $ 488.00
20μg $ 158.00
1mg $ 2340.00
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For research use only.

Synonyms PIGR, PIgR, Poly-Ig Receptor, Polymeric Immunoglobulin Receptor
Species Human
Expression Host E.coli
Sequence Lys19-Ala561
Accession P01833
Calculated Molecular Weight 59.6 kDa
Observed Molecular Weight 59 kDa
Tag N-His
Bio-activity Not validated for activity
Purity > 95% as determined by reducing SDS-PAGE.
Endotoxin < 10 EU/mg of the protein as determined by the LAL method
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Background Polymeric immunoglobulin receptor, also known as&nbsp,PIGR, is a member of the immunoglobulin superfamily&nbsp,and a&nbsp,Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of&nbsp,IgA&nbsp,and&nbsp,IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
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