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Recombinant Human PGA4/Pepsinogen A Protein (Fc Tag) (PKSH030742)

All Size Price Qty
50μg $ 580.00
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For research use only.

Synonyms FLJ58952, FLJ77962, PGA3, PGA4, PGA5
Species Human
Expression Host HEK293 Cells
Sequence Met 1-Ala 388
Accession P00790
Calculated Molecular Weight 67.3 kDa
Observed Molecular Weight 65-70 kDa
Tag C-hFc
Bio-activity Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2, AnaSpec, Catalog # 27114.The specific activity is > 3000 pmoles/min/μg. (Activation description: The enzyme achieves its activity under acidic pH)
Purity > 80 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background PGA4 (Pepsinogen 4; group I); or Pepsinogen A; is a member of the peptidase A1 family. Pepsin is expressed as a pro-form zymogen; pepsinogen; whose primary structure has an additional 44 amino acids. Pepsin is stored as pepsinogen so it will only be released when needed; and does not digest the body's own proteins in the stomach's lining. Five types of zymogens of pepsins; gastric digestive proteinases; are known: pepsinogens A; B; and F; progastricsin; and prochymosin. There are two major groups of pepsinogen; namely pepsinogen A (PGA) and pepsinogen C (PGC) (or progastricsin); and each frequently has isozymogens. The PGA3; PGA4 and PGA5 genes encode identical human pepsinogen A enzymes.
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