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For research use only.
| Synonyms | B7-DC, B7DC, Butyrophilin B7-DC, CD273, PD-1 Ligand 2, PD-L2, PDCD1 Ligand 2, PDCD1L2, PDCD1LG2, PDL2, Programmed Cell Death 1 Ligand 2, Programmed Death Ligand 2 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Leu20-Pro219 |
| Accession | Q9BQ51 |
| Calculated Molecular Weight | 23.6 kDa |
| Observed Molecular Weight | 34-50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver, it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Other Clones
1 Results
Other Formats
1 Results
Biotinylated
