Recombinant Human NAD Kinase/NADK Protein (His Tag) (PKSH032782)

For research use only.
Synonyms | NAD Kinase, NADK, Poly(P)/ATP NAD Kinase |
Species | Human |
Expression Host | E.coli |
Sequence | Ser64-Gly446 |
Accession | AAH01709.1 |
Calculated Molecular Weight | 44.4 kDa |
Observed Molecular Weight | 49 kDa |
Tag | N-His |
Bio-activity | Not validated for activity |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
Formulation | Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 150mM NaCl, 1mM DTT, pH 7.5. |
Reconstitution | Not Applicable |
Background | NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family. It is a widely expressed enzyme, but it is not detected in skeletal muscle. NADK converts Nicotinamide Adenine Dinucleotide (NAD+) into NADP+, through phosphorylating the NAD+ coenzyme. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. The structure of the NADK from the archaean Archaeoglobus fulgidus has been determined. |
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