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Recombinant Human MAP1D Protein (His Tag) (PKSH032749)

All Size Price Qty
50μg $ 198.00
10μg $ 88.00
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For research use only.

Synonyms MAP 1D, MAP1D, METAP1D, MetAP 1D, Metap1l, Methionine Aminopeptidase 1D Mitochondrial, Methionyl Aminopeptidase Type 1D Mitochondrial
Species Human
Expression Host E.coli
Sequence Arg44-Ala335
Accession Q6UB28
Calculated Molecular Weight 35.4 kDa
Observed Molecular Weight 35-40 kDa
Tag N-His & C-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
Reconstitution Not Applicable
Background Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.
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