Recombinant Human LTF Protein(His Tag) (PDMH100285)
For research use only.
| Synonyms | GIG12, Growth inhibiting protein 12, HLF2, Kaliocin 1, Lactoferrin, Lactoferroxin-C, Lactotransferrin, LF, LTF, Neutrophil lactoferrin, Talalactoferrin, TRFL |
| Species | Human |
| Expression Host | Mammalian |
| Sequence | Met1-Lys710 |
| Accession | P02788 |
| Calculated Molecular Weight | 77.9 kDa |
| Observed Molecular Weight | 70-80 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Form | Lyophilized powder |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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