Recombinant Human Interleukin-2/IL-2 Protein (active) (PKSH034200)
For research use only.
| Synonyms | Interleukin-2, IL-2, T-Cell Growth Factor, TCGF, Aldesleukin |
| Species | Human |
| Expression Host | HEK293 cells |
| Sequence | Ala 21-Thr 153 |
| Accession | P60568-1 |
| Calculated Molecular Weight | 15.4 kDa |
| Observed Molecular Weight | 14-22 kDa |
| Tag | None |
| Bio-activity | Human IL-2 Protein, Tag Free stimulates proliferation of CTLL-2 cells. The specific activity of Human IL-2 Protein, Tag Free is > 0.60 x 10^7 IU/mg, which is calibrated against human IL-2 WHO International Standard. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | ≤0.01 EU per μg by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes. |
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