Recombinant Human IL17RB Protein(Fc Tag) (PDMH100214)
For research use only.
| Synonyms | CRL 4, CRL4, Cytokine receptor CRL4, EVI 27, EVI27, IL 17 receptor B, IL 17 receptor homolog 1, IL 17B receptor, IL 17RB, IL 17Rh1, IL17BR, IL17RB, IL17RH1, Interleukin 17 receptor B, Interleukin 17 receptor homolog 1, Interleukin 17 receptor homolog, Interleukin 17B receptor, MGC5245 |
| Species | Human |
| Expression Host | Mammalian |
| Sequence | Arg18-Pro292 |
| Accession | Q9NRM6 |
| Calculated Molecular Weight | 55.1 kDa |
| Observed Molecular Weight | 60-80 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. |
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