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Recombinant Human IL-1R8/IL1RAPL1 Protein (His Tag) (PKSH033634)

All Size Price Qty
50μg $ 438.00
10μg $ 198.00
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For research use only.

Synonyms IL1R, OPHN, TIGIRR, MRX, IL1RAPL1, IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2, IL1RAPL-1, IL-1RAPL-1, IL-1-RAPL-1, Interleukin-1 Receptor Accessory Protein-Like 1, Oligophrenin-4, Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2, X-Linked Interleukin-1 Receptor Accessory Protein-Like 1
Species Human
Expression Host HEK293 Cells
Sequence Leu19-Val360
Accession Q9NZN1
Calculated Molecular Weight 40 kDa
Observed Molecular Weight 50-60 kDa
Tag C-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background Interleukin-1 receptor accessory protein-like 1; also known as IL1RAPL1; can be detected at low levels in heart; skeletal muscle; ovary; skin; amygdala; caudate nucleus; corpus callosum; hippocampus; substantia nigra and thalamus. IL1RAPL1 functions as a homodimer; it interacts with NCS1; PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation; it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.
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