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Recombinant Human H1F0/Histone H1 Protein (His Tag) (PKSH031355)

All Size Price Qty
100μg $ 760.00
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For research use only.

Synonyms CPN60, GROEL, H10, H1FV, HLD4, HSP60, HSP65, HSPD1, HuCHA60, SPG13
Species Human
Expression Host E.coli
Sequence Met 1-Lys 194
Accession P07305
Calculated Molecular Weight 22.4 kDa
Observed Molecular Weight 27 kDa
Tag N-His
Bio-activity Not validated for activity
Purity > 92 % as determined by reducing SDS-PAGE.
Endotoxin Please contact us for more information.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 50mM Tris, 600mM NaCl, 1mM DTT, pH 8.5
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the &quot;beads on a string&quot; sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-terminal and C-terminal tails. These tails are moderately conserved among species, but differ among variants, suggesting a specific function for each H1 variant. Studies on the role of particular subtypes at specific developmental stages in lower eukaryotes, but also in vertebrates suggest that specific subtypes of H1 participate in particular systems of gene regulation.
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