Recombinant Human GSTAL Protein(Trx Tag) (PDEH100656)
For research use only.
| Synonyms | GST, GTH, GSTA, HA subunit, GST HA subunit, GST class alpha member, GST class-alpha member, Glutathione S transferase A, Glutathione S alkyltransferase A, S (hydroxyalkyl)glutathione lyase A, GSTA1, GST-epsilon, GST2, GSTA1-1, GTH1, Glutathione S alkyltransferase A1, GST class-alpha member 1, HA subunit 1, S (hydroxyalkyl)glutathione lyase A1, Glutathione S transferase A1, GST class alpha member 1, GST epsilon, GST HA subunit 1, GSTA1 1, Glutathione S transferase 2, Glutathione S transferase Ha subunit 1, GST class-alpha member 1, GST epsilon, GST HA subunit 1, GST2, GSTA1, GSTA1-1, GST-epsilon, GTH1, HA subunit 1, MGC131939 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met1-Phe222 |
| Accession | P08263 |
| Calculated Molecular Weight | 44.4 kDa |
| Observed Molecular Weight | 39 kDa |
| Tag | N-Trx |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
| Background | GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1). GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy. |
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