Recombinant Human Growth Arrest-Specific Protein 7/GAS7 Protein (His Tag) (PKSH032510)
For research use only.
| Synonyms | GAS-7, GAS7, Growth Arrest-Specific Protein 7, KIAA0394 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Ile412 |
| Accession | O60861 |
| Calculated Molecular Weight | 49.4 kDa |
| Observed Molecular Weight | 57 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 500mM NaCl, 50% glycerol,1mM EDTA, pH7.4. |
| Reconstitution | Not Applicable |
| Background | Growth Arrest-Specific Protein 7 (GAS7) is expressed primarily in terminalaly differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Inhibition of GAS7 production in terminally differentiating cultures of embryonic murine cerebullum impedes neurite outgrowth. The hyper-expression of GAS7 may play an major role in the initiation and development of huaman osteosarcoma. |
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