Recombinant Human FGF2 Protein(GST Tag) (PDEH100489)
For research use only.
| Synonyms | HBGF, FGF, BFGF, FGF-2, FGFB, HBGF-2, Basic FGF, FGF2, Basic Fibroblast Growth Factor, B-FGF, FGF-β, Fibroblast Growth Factor 2, heparin-binding growth factor 2, prostatropin, BFGF, B-FGF, FGF-2, FGFB, fibroblast growth factor 2, HBGF-2, heparin-binding growth factor 2, prostatropin, basic, Basic fibroblast growth factor bFGF, FGF 2, FGF B, FGF2 basic, Fibroblast growth factor, Fibroblast growth factor 2 (basic), HBGF 2, HBGF2, HBGH 2, HBGH2, Heparin binding growth factor 2 precursor, heparin-binding growth factor 2, FGF-β |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Pro143-Ser288 |
| Accession | P09038 |
| Calculated Molecular Weight | 42.1 kDa |
| Observed Molecular Weight | 48 kDa |
| Tag | N-GST |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
| Background | Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies. |
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