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Recombinant Human ERP57/PDIA3 Protein (His Tag) (PKSH032955)

All Size Price Qty
50μg $ 358.00
10μg $ 158.00
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For research use only.

Synonyms 58 kDa glucose-regulated protein, Disulfide isomerase ER-60, ER protein 57, PDIA3 protein, Protein disulfide-isomerase A3
Species Human
Expression Host HEK293 Cells
Sequence Ser25-Leu505
Accession P30101
Calculated Molecular Weight 55.3 kDa
Observed Molecular Weight 60 kDa
Tag C-His
Bio-activity Not validated for activity
Purity > 85 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Reconstitution Not Applicable
Background PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
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