Recombinant Human ECF/CCL11 Protein(Sumo Tag) (PDEH100544)
For research use only.
| Synonyms | C-C motif chemokine 11, CCL 11, CCL11, CCL11, chemokine (C-C motif) ligand 11, Chemokine C C motif ligand 11, Chemokine CC Motif Ligand 11, Chemokine ligand 11, Eosinophil chemotactic protein, Eotaxin, eotaxin-1, MGC22554, SCYA 11, SCYA11, Small inducible cytokine A11, Small inducible cytokine subfamily A (Cys Cys) member 11, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin), Small inducible cytokine subfamily A member 11, Small-inducible cytokine A11 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Gly24-Pro97 |
| Accession | P51671 |
| Calculated Molecular Weight | 24.1 kDa |
| Observed Molecular Weight | 28 kDa |
| Tag | N-Sumo |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. |
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