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Recombinant Human dUTPase Protein (PKSH032364)

All Size Price Qty
50μg $ 198.00
10μg $ 88.00
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For research use only.

Synonyms DUT, Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial, dUTP Pyrophosphatase, dUTPase
Species Human
Expression Host E.coli
Sequence Met 1-Asn164
Accession P33316-2
Calculated Molecular Weight 17.7 kDa
Observed Molecular Weight 17 kDa
Tag None
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Not Applicable
Background Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial (dUTPase) belongs to the dUTPase family. dUTPase exits as a homotrimer and is involved in nucleotide metabolism. dUTPase produces dUMP; the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. The dUTPase increase in PCR product yield; length and fidelity enables further down-stream applications. These effects make dUTPase useful in PCR fidelity and yield-sensitive applications. dUTPase is specific for dUTP and is critical for the fidelity of DNA replication and repair.
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