Recombinant Human DKK-3 Protein(His Tag) (PDMH100318)
For research use only.
| Synonyms | UNQ, PRO, Dickkopf-Related Protein, hDkk, Dickkopf, DKK, DKK3, REIC, RIG, Dickkopf-3, Dickkopf-Related Protein 3, Dkk-3, hDkk-3, UNQ258, PRO295, Dickkopf 3, Dickkopf 3 homolog, Dickkopf 3 homolog (Xenopus laevis), Dickkopf homolog 3, Dickkopf related protein 3, Dickkopf related protein 3 Precursor, Dickkopf WNT signaling pathway inhibitor 3, Dickkopf3, DKK 3, hDkk 3, hDkk3, homolog of, Regulated in glioma, RIG-like 5-6, RIG-like 7-1, Xenopus |
| Species | Human |
| Expression Host | Mammalian |
| Sequence | Ala22-Ile350 |
| Accession | Q9UBP4 |
| Calculated Molecular Weight | 36.0 kDa |
| Observed Molecular Weight | 50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1 , DKK2 , DKK3 and DKK4. It is a secreted protein , and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway. |
Other Clones
{{antibodyDetailsPage.numTotal}} Results
-
{{item.title}}
Citations ({{item.publications_count}}) Manual MSDS
Cat.No.：{{item.cat}}
{{index}} {{goods_show_value}}
Other Formats
{{formatDetailsPage.numTotal}} Results
-
{{item.title}}
Citations ({{item.publications_count}}) Manual MSDS
Cat.No.：{{item.cat}}
{{index}} {{goods_show_value}}
-
IF：{{item.impact}}
Journal：{{item.journal}} ({{item.year}})
DOI：{{item.doi}}Reactivity：{{item.species}}
Sample Type：{{item.organization}}
-
Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}
