Recombinant Human CXCL5 Protein(Trx Tag) (PDEH100525)
For research use only.
| Synonyms | AMCFII, C-X-C motif chemokine 5, C-X-C motif chemokine ligand 5, chemokine (C-X-C motif) ligand 5, Cxcl5, CXCL5, ENA 78, ENA-78 (8-78), ENA-78(1-78), ENA-78(9-78), ENA78, Epithelial derived neutrophil activating protein 78, Epithelial-derived neutrophil-activating protein 78, Lipopolysaccharide-induced CXC chemokine, Neutrophil activating peptide ENA 78, Neutrophil-activating peptide ENA-78, neutrophil-activating protein 78, SCYB5, Small inducible cytokine B5, small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78), small inducible cytokine subfamily B, member 5, Small-inducible cytokine B5 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ala37-Asn114 |
| Accession | P42830 |
| Calculated Molecular Weight | 28 kDa |
| Observed Molecular Weight | 30 kDa |
| Tag | N-Trx |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | CXCL5 (C-X-C Motif Chemokine Ligand 5) is a Protein Coding gene. Diseases associated with an CXCL5 include Pediatric Ulcerative Colitis and Acute Cervicitis. Among its related pathways are Peptide ligand-binding receptors and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. GO annotations related to this gene include chemokine activity and CXCR chemokine receptor binding. An important paralog of this gene is CXCL6.This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. |
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