Recombinant Human CXCL10 protein (His Tag) (PDEH100886)
For research use only.
| Synonyms | 10 kDa Interferon Gamma-Induced Protein, C-X-C Motif Chemokine 10, CXCL10, Gamma-IP10, INP10, IP-10, SCYB10, Small-Inducible Cytokine B10 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Val22-Pro98 |
| Accession | P02778 |
| Calculated Molecular Weight | 8.4 kDa |
| Observed Molecular Weight | 12 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity. |
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