Recombinant Human CXCL1 Protein(GST Tag) (PDEH100462)
For research use only.
| Synonyms | CXCL, SCYB, Secretory protein N, CINC, NAP, CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1, GRO alpha, CINC-1, C-X-C Motif Chemokine 1, GRO-A, GRO-Alpha(1-73), Growth-Regulated Alpha Protein, GRO-α: MGSAα, Melanoma Growth Stimulatory Activity, NAP3, Neutrophil-Activating Protein 3, Platelet-derived growth factor-inducible protein KC, Secretory protein N51, GRO, alpha, alpha), chemokine (C-X-C motif) ligand 1, Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, C-X-C motif chemokine ligand 1, Cytokine-induced neutrophil chemoattractant 1, Fibroblast secretory protein, Gro 1, Gro A, GRO protein, Gro1 oncogene, GRO1 oncogene (melanoma growth stimulating activity, GRO1 oncogene (melanoma growth-stimulating activity), GRO-alpha(6-73), homolog of, KC chemokine, melanoma growth stimulatory activity alpha, member 1, MGSA alpha, mouse, N51, Scyb 1, Small inducible cytokine subfamily B |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ala35-Asn107 |
| Accession | P09341 |
| Calculated Molecular Weight | 43.8 kDa |
| Observed Molecular Weight | 38 kDa |
| Tag | N-GST |
| Bio-activity | Not validated for activity |
| Purity | > 85% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
| Background | Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis. |
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