Recombinant Human CD74 protein (His Tag) (PDEH100704)
For research use only.
| Synonyms | CD 74, CD74 antigen (invariant polypeptide of major histocompatibility complex, CD74 molecule, CLIP, DHLAG, Gamma chain of class II antigens, HG2A, HLA class II histocompatibi, class II antigen-associated), class II invariant chain, major histocompatibility complex |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Gln73-Met296 |
| Accession | P04233 |
| Calculated Molecular Weight | 26.6 kDa |
| Observed Molecular Weight | 30-33 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF. |
Other Clones
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