Recombinant Human Carbonic Anhydrase 7/CA7 Protein (His Tag) (PKSH032164)
For research use only.
| Synonyms | CA-VII, CA7, CAVII, Carbonate Dehydratase VII, Carbonic Anhydrase 7, Carbonic Anhydrase VII |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Ala264 |
| Accession | P43166 |
| Calculated Molecular Weight | 30.7 kDa |
| Observed Molecular Weight | 31 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| Reconstitution | Not Applicable |
| Background | Carbonic Anhydrase 7 (CA7) is a member of the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Furthermore; Alpha-carbonic anhydrase is associated with many biological processes; including calcification; respiration; bone resorption; acid-base balance and the formation of aqueous humor. CA7 is activated by histamine; L-adrenaline; L- and D-histidine; and L- and D-phenylalanine; but it is inhibited coumarins; sulfonamide derivatives such as acetazolamide (AZA) by saccharin and Foscarnet. |
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