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For research use only.
Synonyms | C10orf54, Platelet receptor Gi24, SISP1, Sisp-1, Stress-induced secreted protein-1 |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Phe33-Ala194(Asp187Glu) |
Accession | Q9H7M9 |
Calculated Molecular Weight | 19.2 kDa |
Observed Molecular Weight | 30-50 kDa |
Tag | C-His |
Bio-activity | Not validated for activity |
Form | Lyophilized powder |
Purity | > 95% as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Background | platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively. |
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