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Recombinant Human ATG4A Protein (His Tag) (PKSH032099)

All Size Price Qty
50μg $ 288.00
10μg $ 128.00
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For research use only.

Synonyms APG4A, ATG4A, AUT-Like 2 Cysteine Endopeptidase, AUTL2, Autophagin-2, Autophagy-Related Cysteine Endopeptidase 2, Autophagy-Related Protein 4 Homolog A, Cysteine Protease ATG4A, hAPG4A
Species Human
Expression Host E.coli
Sequence Met 1-Val398
Accession Q8WYN0
Calculated Molecular Weight 47.5 kDa
Observed Molecular Weight 40-55 kDa
Tag N-His
Bio-activity Not validated for activity
Purity > 80 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Not Applicable
Background Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
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