Recombinant Histone H2A.Z Monoclonal Antibody (AN301262L)

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	100μL	$ 320.00	- +
	50μL	$ 211.00	- +

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Verified Samples	Verified Samples in IHC: Human breast carcinoma
Dilution	IHC 1:200-1:1000
Isotype	IgG,κ
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IHC
Clonality	Monoclonal;Recombinant
Immunogen	Recombinant Human Histone H2A.Z protein
Abbre	Histone H2A.Z
Synonyms	H2AFZ, H2AZ, H2AZ1, Histone H2A.Z
Swissprot	P0C0S5
Cellular Localization	Nucleus, Chromosome.
Concentration	0.2 mg/mL
Buffer	PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Purification Method	Protein A
Research Areas	Epigenetics and Nuclear Signaling
Clone No.	6B1
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	Ice bag
background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

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Unconjugated