Recombinant GOLM1/GP73 Monoclonal Antibody (AN300431P)

For research use only.
Verified Samples | Verified Samples in IHC: Human uterus, Human liver |
Dilution | IHC-P 1:100-1:500 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC-P |
Clonality | Monoclonal |
Immunogen | Recombinant Human GOLM1/GP73 protein |
Abbre | GOLM1 |
Synonyms | HEL, UNQ, PRO, GOLM, Golgi Phosphoprotein, Golgi Membrane Protein, Golgi Membrane Protein GP, C9orf, GOLPH, bA379P, GOLM1, C9orf155, GOLPH2, GP73, HEL46, PSEC0257, bA379P1.3, Golgi Membrane Protein 1, Golgi Membrane Protein GP73, Golgi Phosphoprotein 2, PSEC0242, UNQ686, PRO1326 |
Swissprot | |
Tissue Specificity | Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. |
Concentration | 1 mg/mL |
Buffer | 0.2 μm filtered solution in PBS |
Purification Method | Protein A |
Research Areas | Signal Transduction |
Clone No. | 4B8 |
Conjugation | Unconjugated |
Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Shipping | Ice bag |
background | The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene. |
Other Clones
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Unconjugated
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