Recombinant Ephrin-A1/EFNA1 Monoclonal Antibody (AN300352P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human pancreas |
| Dilution | IHC-P 1:100-1:500 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human Ephrin-A1/EFNA1 protein |
| Abbre | EFNA1 |
| Synonyms | EPLG, TNF Alpha-Induced Protein, Immediate Early Response Protein B, EPH-Related Receptor Tyrosine Kinase Ligand, Tumor Necrosis Factor Alpha-Induced Protein, EFNA, TNFAIP, Ephrin-A, EPH-Related Receptor Tyrosine Kinase Ligand 1, Ephrin-A1, Immediate Early Response Protein B61, LERK-1, TNF Alpha-Induced Protein 4, Tumor Necrosis Factor Alpha-Induced Protein 4, EPLG1, LERK1, TNFAIP4, EFNA1, B61, ECKLG, EFL 1, EFL1, EFNA 1, EPH related receptor tyrosine kinase ligand 1, Ephrin A1, EphrinA1, EPLG 1, LERK 1, Ligand of eph related kinase 1, OTTHUMP00000033242, OTTHUMP00000033271, secreted form, TNFAIP 4, Tumor necrosis factor alpha induced protein 4 |
| Swissprot | |
| Tissue Specificity | Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level). |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Cardiovascular, Neuroscience, Signal Transduction |
| Clone No. | 10F14 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization. |
Other Clones
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Unconjugated
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