Recombinant chiken IL2/IL-2/Interleukin-2 protein (His Tag) (PDEO100024)
For research use only.
| Synonyms | IL2, IL-2, TCGF, lymphokine, IL3, IL4, IL5, IL6, Aldesleukin, IL-2lymphokine, interleukin-2, Proleukin, interleukin 2, involved in regulation of T-cell clonal expansion, T cell growth factor, T-cell growth factor, IL 2, IL2, Interleukin 2, interleukin2, Involved in regulation of T cell clonal expansion, Lymphokine, POIL2, T Cell Growth Factor, TCGF |
| Species | Chicken |
| Expression Host | E.coli |
| Sequence | Ala23-Lys143 |
| Accession | O73883 |
| Calculated Molecular Weight | 13.2 kDa |
| Observed Molecular Weight | 14 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions,including T cell proliferation,interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells. |
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