Recombinant CD302/CLEC13A Monoclonal Antibody (AN300166P)

For research use only.
Verified Samples | Verified Samples in IHC: Mouse spleen |
Dilution | IHC-P 1:100-1:500, |
Isotype | IgG |
Host | Rabbit |
Reactivity | Mouse |
Applications | IHC-P |
Clonality | Rabbit Monoclonal |
Immunogen | Recombinant Mouse CD302 / CLEC13A protein |
Abbre | CD302 |
Synonyms | 1110055L24Rik, AI159627, Clec13a, Cd302, DCL1 |
Swissprot | |
Concentration | 1 mg/mL |
Buffer | 0.2 μm filtered solution in PBS |
Purification Method | Protein A |
Clone No. | 5H5 |
Conjugation | Unconjugated |
Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Shipping | Ice bag |
background | CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function. |
Other Clones
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Other Formats
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Unconjugated
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